NOBLE PANACEA 
The Exceptional Chronobiology Sleep Mask Refill

The Chronobiology Sleep Mask harnesses the power of the intelligent OSMV™ Technology for a programmed release sequence of high concentrated active ingredients that is calibrated to the overnight circadian rhythm process. Active ingredients are delivered to the skin to enhance the natural detox, repair, and regeneration processes. Skin is instantly hydrated with long-lasting nourishment, boosted cellular renewal reduces the appearance of fine lines and wrinkles, while skin appears purified and revitalized, with glowing luminosity.

The skin synchronized ingredient release program- delivers pre, pro and post biotics, exfoliating PHA, a retinol and peptide pairing, enriched with ceramide and 2D hyaluronic acid- enriched with a blend of five precious botanical oils. It works throughout the night to transform skin while sleeping, a sophisticated piece of science for unparalleled skin results.

All skin types. Non-comedogenic. Dermatologist-approved.

- Instant and deep hydration for intense nourishment

- Skin's radiance is revived overnight, and skin is illuminated

- Skin is more plump, firmer, and revitalized

- The appearance of fine lines and wrinkles are reduced

- Stressed skin is soothed, calmed and repaired

- Skin feels more protected, and the skin barrier is restored and supported

- Skin tone and texture is more uniform

- Skin feels and look reset, detoxified and rebalanced

- Dark spots and pigmentation appear diminished and lightened, skin tone appears more even.

- Winner of GLAMOUR Beauty Award 2022, ELLE Hong Kong Beauty Awards 2023

- At the core of Noble Panacea’s formulas is the Organic Super Molecular Vessel™ born from Sir Fraser Stoddart’s award-winning research and discovery. Lending itself perfectly to highly efficacious skincare, this technology protects and preserves active ingredients’ potency on the molecular level while precisely releasing it into the skin over a continual extent of time. Each OSMV™ is individually programmed to deliver active ingredients to the appropriate cell for absorption at the optimal moment at the optimal sequence. The targeted treatment of this Perpetual Potency™ triggers the continual regenerative capacity of skin cells, ensuring the ultimate complexion protection and maximum skin radiance well beyond application.

- All formulas are free of phthalates, mineral oil, parabens, silicone, GMO’s, SLS & SLES, alcohol, artificial fragrance, nitrates, palm oil, petrolatum, artificial colors, gluten, and cruelty (no animal testing)

Apply 1 to 2 times a week or according to your skin needs, to face and neck, as the last step of your skincare ritual, before sleeping.

WATER/EAU/AQUA, ARGANIA SPINOSA (ARGAN) KERNEL OIL, GLYCERIN, OLIGOSACCHARIDE FATTY ACID ESTERS (OSMV), SQUALANE, ASCORBYL GLUCOSIDE, LACTOBACILLUS FERMENT, SUCROSE STEARATE, CETEARYL ALCOHOL, NIACINAMIDE, POTASSIUM CETYL PHOSPHATE, VITIS VINIFERA (GRAPE) SEED OIL, SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL, DIPALMITOYL HYDROXYPROLINE, ALPHA-GLUCAN OLIGOSACCHARIDE, PROPANEDIOL, ROSA DAMASCENA (ROSE) FLOWER WATER, ALOE BARBADENSIS LEAF JUICE, BUTYROSPERMUM PARKII (SHEA) BUTTER, JOJOBA ESTERS, STEARYL ALCOHOL, LACTIC ACID, OPUNTIA FICUS-INDICA (PRICKLY PEAR) SEED OIL, NIGELLA SATIVA (BLACK CUMIN) SEED OIL, CERAMIDE NP, HYDROLYZED SODIUM HYALURONATE, SODIUM HYALURONATE, RETINOL, GLUCONOLACTONE, PERSEA GRATISSIMA (AVOCADO) OIL, ACETYL HEXAPEPTIDE-8, PALMITOYL TRIPEPTIDE-38, SH-OLIGOPEPTIDE-1, SH-OLIGOPEPTIDE-2, SH-POLYPEPTIDE-1, SH-POLYPEPTIDE-11, SH-POLYPEPTIDE-9, CENTELLA ASIATICA (GOTU KOLA) LEAF EXTRACT, MAGNESIUM ASCORBYL PHOSPHATE, GLYCOLIC ACID, CAMELLIA SINENSIS (GREEN TEA) LEAF EXTRACT, BAKUCHIOL, CAFFEINE (COFFEA ARABICA), PANAX GINSENG ROOT EXTRACT, ACETYL GLUTAMINE, LECITHIN, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, ALLANTOIN, XANTHAN GUM, CARNITINE, RICE AMINO ACIDS, VITIS VINIFERA (GRAPE) SEED EXTRACT, ASCORBYL TETRAISOPALMITATE, GLYCERYL LINOLEATE, PHYTIC ACID, ASCORBYL PALMITATE, PANTHENOL, TOCOPHEROL, TOCOPHERYL ACETATE, GLYCERYL LINOLENATE, ORYZA SATIVA (RICE) BRAN EXTRACT, HELIANTHUS ANNUUS (SUNFLOWER) EXTRACT, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, UBIQUINONE, POTASSIUM HYDROXIDE, PHOSPHOLIPIDS, BACILLUS/FOLIC ACID FERMENT FILTRATE EXTRACT, HYDROXYPROPYL CYCLODEXTRIN, CAPRYLYL GLYCOL, ETHYLHEXYLGLYCERIN, PHENOXYETHANOL, SODIUM BENZOATE

We do not believe that CLEAN products are a must or the answer to every skin care problem. But we want to provide a quick guide for those who want to avoid certain ingredients.

Our Clean Beauty concept is primarily defined by the ingredients you won't find in the products with the CLEAN icon:

BHA (butylated hydroxyanisole), BHT (butylated hydroxytoluene), chemical sunscreens, EDTA, ethanolamines, ethoxylated ingredients (Ceteareth-20, emulsifying wax, PEGS, polysorbate-20, polysorbate-40, steareth-20, sulfates), formaldehyde, methylchloroisothiazolinone and methylisothiazolinone, methylcellulose or 2-methoxyethanol, nitro- and polycyclic musk, parabens, petrolatum and paraffin, phthalates, resorcinol, silicones, animal by-products (with the exception of lanolin and beeswax), toluene, triclosan and triclocarban.

With this icon you can see at a glance which products meet the standard of our CLEAN Guide.

Read more in the STUDIO about THE NICHE CLEAN GUIDE!